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Pascale S. Guiton, Ph.D. Faculty Profile

Photo of Pascale Guiton

Pascale  S.  Guiton, Ph.D.

Assistant Professor

Department of Biological Sciences

  • E-mail:
  • Phone: 510-885-3412
  • Office: SC-S352 / Laboratory SC-S350
  • Office Hours: Fall quarter 2017 W & F 2:30pm-4:00pm or by appointment
  • Vitae: View my CV
  • Home Page:
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My laboratory studies the biology of Toxoplasma gondii, a ubiquitous pathogen, and other related pathogens. One third of the world population is believed to have been infected with Toxoplasma gondii. Specifically, as a molecular microbiology and microbial pathogenesis laboratory, we use classic and novel molecular techniques to identify and characterize new determinants of Toxoplasma pathogenicity. We are also interested in understanding the molecular factors associated with microbial biofilm formation and their roles in biofilm-associated infections, such as Catheter-Associated Urinary Tract Infections (CAUTIs).

I am currently recruiting graduate students and undergraduates interested in research in Molecular Microbiology, Parasitology, and Medical Microbiology; as a means to further expand their scientific interests. No previous laboratory experience required; freshmen and sophomores are highly encouraged to apply. 

For more information about our group, the research we conduct, and how to be part of the team,  please visit

  • Postdoctoral Fellowship, Laboratory of John Boothroyd, Ph. D., Stanford University School of Medicine (2012-2017)
  • Ph.D., Biological Sciences and Medicine , Washington University in St. Louis (2012)
  • B. Sc., Biological Sciences, Georgia State University (2005)
Fall Semester 2018
Course #SecCourse TitleDaysFromToLocationCampusTextbook Info
BIOL 23001Clinical MicrobiologyMW9:30AM10:45AMMI-2064Hayward Campus View Books
BIOL 2301AClinical MicrobiologyW11:00AM1:50PMSC-S307Hayward Campus View Books
BIOL 2301BClinical MicrobiologyW2:00PM4:50PMSC-S307Hayward Campus View Books
BIOL 69002Independent StudyARRARRHayward Campus View Books
BIOL 69003Independent StudyARRARRHayward Campus View Books
BIOL 69102University ThesisARRARRHayward Campus View Books

  • Guiton PS, Sagawa J, Fritz H, JC Boothroyd. An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells. Plos One 2017 12(3): e0173018
  • Frank KL, Guiton PS, Barnes AM, Manias DA, Chuang-Smith ON, Kohler PL, Spaulding AR, Hultgren SJ, Schlievert, PM, Dunny GM. AhrC and Eep are biofilm infection-associated virulence factors in Enterococcus faecalis. Infect Immun. 2013 81(5):1696-708.
  • Guiton PS, Hannan TJ, Ford B, Caparon MG, Hultgren SJ. Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections. Infect. Immun. 2013 81(1):329-39. **Article of Significant Interest Selected from This Issue by the Editor**
  • Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, Henderson JP, Caparon MG, Hultgren SJ. Combinatorial small-molecular therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob. Agents Chemother. 2012 56(9):4738-45.
  • Nielsen HV, Guiton PS, Kline KA, Port GC, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. The metal ion-dependent adhesion site motif of EbpA pilin mediates pilus function in catheter-associated urinary tract infection. Mbio. 2012 3(4):e00177-12.
  • Guiton PS, Hung CS, Hancock L., Caparon MG, Hultgren SJ. Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infection. Infect. Immun. 2010 78(10):4166-4175. **Article of Significant Interest Selected from This Issue by the Editor* 
  • Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ.
  • Contribution of autolysin and sortase A during Enterococcus faecalis DNA-dependent biofilm development. Infect. Immun. 2009 77(9):3626-38.







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