Pascale S. Guiton, Ph.D. Faculty Profile

Photo of Pascale Guiton

Pascale  S.  Guiton, Ph.D.

Assistant Professor

Department of Biological Sciences

  • E-mail:
  • Phone: 510-885-3412
  • Office: SC-S352 / Laboratory SC-S350
  • Office Hours: Spring 2019 Tu 3:00 pm-4:00 pm, Th 11:00 am - 12:00 pm or by appointment
  • Vitae: View my CV
  • Home Page:
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My laboratory studies the biology of Toxoplasma gondii, a ubiquitous pathogen, and other related pathogens. One-third of the world population is believed to have been infected with Toxoplasma gondii. Specifically, as a molecular microbiology and microbial pathogenesis laboratory, we use classic and novel molecular techniques to identify and characterize new determinants of Toxoplasma pathogenicity. We are also interested in understanding the molecular factors associated with microbial biofilm formation and their roles in biofilm-associated infections, such as Catheter-Associated Urinary Tract Infections (CAUTIs).

Students, including Freshmen and Sophomores, interested in research in Molecular Microbiology, Parasitology, and Medical Microbiology; as a means to further expand their scientific interests, are welcome to visit our website for more information on our group, the research we conduct, and how to be part of the team. No previous laboratory experience required!

  • Postdoctoral Fellowship, Laboratory of John Boothroyd, Ph. D., Stanford University School of Medicine (2012-2017)
  • Ph.D., Biological Sciences and Medicine , Washington University in St. Louis (2012)
  • B. Sc., Biological Sciences, Georgia State University (2005)

Not teaching this semester.

  • Cao B and Guiton PS. Important human parasites of the tropics. Frontiers for Young Minds 2018 6:58. doi:10.3389/frym.2018.00058
  • Guiton PS, Sagawa J, Fritz H, JC Boothroyd. An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells. Plos One 2017 12(3): e017301
  • Frank KL, Guiton PS, Barnes AM, Manias DA, Chuang-Smith ON, Kohler PL, Spaulding AR, Hultgren SJ, Schlievert, PM, Dunny GM. AhrC and Eep are biofilm infection-associated virulence factors in Enterococcus faecalis. Infect Immun. 2013 81(5):1696-708.
  • Guiton PS, Hannan TJ, Ford B, Caparon MG, Hultgren SJ. Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections. Infect. Immun. 2013 81(1):329-39. Article of Significant Interest Selected from This Issue by the Editor
  • Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, Henderson JP, Caparon MG, Hultgren SJ. Combinatorial small-molecular therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob. Agents Chemother. 2012 56(9):4738-45.
  • Nielsen HV, Guiton PS, Kline KA, Port GC, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. The metal ion-dependent adhesion site motif of EbpA pilin mediates pilus function in catheter-associated urinary tract infection. Mbio. 2012 3(4):e00177-12.
  • Guiton PS, Hung CS, Hancock L., Caparon MG, Hultgren SJ. Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infection. Infect. Immun. 2010 78(10):4166-4175. **Article of Significant Interest Selected from This Issue by the Editor* 
  • Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ. Contribution of autolysin and sortase A during Enterococcus faecalis DNA-dependent biofilm development. Infect. Immun. 2009 77(9):3626-38.







Coordinator of CSU East Bay Biology Seminar Series

CSUPERB Don Eden Graduate Student Research Award Committee.

Faculty Consensus Group (FCG) CSUPERB Committee – representative for CSU East Bay.

Coordinator of the First Annual Research Symposium of CSU East Bay Department of Biological Sciences, Hayward C

Biology Club Faculty Co-Adviser, California State University East Bay, Hayward, CA.