Claudia Uhde-Stone Faculty Profile

Photo of Claudia Uhde-Stone

Claudia  Uhde-Stone


Department of Biological Sciences

In my lab, undergraduate and graduate students collaborate to unravel the molecular mechanisms that underlie plants’ abilities to adapt, communicate, learn, and potentially live forever.

Specific research questions we are currently pursuing are:

• How can some plants grow where other plants can not?

• How do plant roots and shoots communicate with each other?

• Do plants have a memory, and can they learn?

• How can some plants live forever?

To explore these research questions, we are using a wide variety of experimental approaches that include next-generation sequencing, genome editing with CRISPR-Cas, qRT-PCR, proteomics, bioinformatics, and plant learning set-ups. If you are interested in our research, feel free to e-mail me!

  • PhD, University of Bielefeld, Germany
Spring Semester 2024
Course #SecCourse TitleDaysFromToLocationCampus
BIOL 140A03Cell & Molecular BiologyTTH9:30AM10:45AMMI-2032Hayward Campus
BIOL 140A04Cell & Molecular BiologyTTH9:30AM10:45AMMI-2032Hayward Campus
BIOL 140A05Cell & Molecular BiologyTTH9:30AM10:45AMMI-2032Hayward Campus
BIOL 42401BioinformaticsTU2:00PM2:50PMSC-S205Hayward Campus
BIOL 42409SSBioinformaticsM2:00PM2:50PMSC-N125HAYWARD
BIOL 4241ABioinformaticsTTH3:00PM4:40PMSC-S138Hayward Campus
BIOL 4249BSSBioinformaticsMW3:00PM4:40PMVBT-0221HAYWARD
BIOL 49301Directed ResearchARRARRHayward Campus
BIOL 49303Directed ResearchARRARRHayward Campus
BIOL 62001Functional GenomicsM10:00AM10:50AMSC-N406Hayward Campus
BIOL 6201AFunctional GenomicsMW11:00AM1:30PMSC-N406Hayward Campus
BIOL 68101ResearchARRARRHayward Campus

Uhde-Stone, C. (2017). White lupin: a model system for understanding plant adaptation to low phosphorus availability Legume Nitrogen Fixation in Soils with Low Phosphorus Availability (pp. 243-280): Springer.

Amadi, M., Cole, J., Li, K., Chalkley, R. J., Burlingame, A., Uhde-Stone, C. (2017). Unraveling White Lupin’s Signal Transduction in Response to Phosphorus Deficiency Using iTRAQ Labeling, Phosphopeptide Enrichment, and Tandem Mass Spectrometry. The FASEB Journal, 31(1_supplement), 617.611-617.611.

Afshari A, Uhde-Stone C, Lu B. (2015). A cooled CCD camera-based protocol provides an effective solution for in vitromonitoring of luciferase. Biochem Biophys Res Commun. 458(3):543-8.

Afshari A, Uhde-Stone C, Lu B. (2014) Live visualization and quantification of pathway signaling with dual fluorescent and bioluminescent reporters. Biochem Biophys Res Commun. 448(3):281-6.

Uhde-Stone C, Sarkar N, Antes T, Otoc N, Kim Y, Jiang YJ, Lu B. (2014). A TALEN-based strategy for efficient bi-allelic miRNA ablation in human cells. RNA. 2014 Jun; 20(6):948-55.

Uhde-Stone C, Cheung E, Lu B.(2014) TALE activators regulate gene expression in a position- and strand-dependent manner in mammalian cells. Biochem Biophys Res Commun. 443(4):1189-94.

Uhde-Stone C, Gor N, Chin T, Huang J, Lu B.(2013). A do-it-yourself protocol for simple transcription activator-like effector assembly. Biol Proced Online. 15(1):3.

O'Rourke JA, Yang SS, Miller SS, Bucciarelli B, Liu J, Rydeen A, Bozsoki Z, Uhde-Stone C, Tu ZJ, Allan D, Gronwald JW, Vance CP. (2013). An RNA-Seq transcriptome analysis of orthophosphate-deficient white lupin reveals novel insights into phosphorus acclimation in plants. Plant Physiol. 161(2):705-24.

Uhde-Stone C, Huang J, Lu B. (2012) A robust dual reporter system to visualize and quantify gene expression mediated by transcription activator-like effectors. Biol Proced Online. 8;14(1):8.

Liu, M., Uhde-Stone, C., and C. Goudar. 2011. Progress curve analysis of qRT-PCR reactions using the logistic growth equation. Biotechnol. Prog.27: 1407-1414.

Rath, M., Salas, J., Parhy, B., Norton, R., Hatlstad, G., Kwon, J., Allan, D.L., C.P. Vance, and C. Uhde-Stone. 2010. Identification of genes induced in proteoid roots of white lupin under nitrogen and phosphorus deficiency, with functional characterization of a formamidase. Plant and Soil334:137-150

Norton, R., Uhde-Stone, C., and M. Rath. 2007. Array analysis to assess effects of RNAi-based silencing. JSM Proceedings, Biometrics Section [CD-ROM], Alexandria, VA: American

Statistical Association: 263-268

Uhde-Stone, C., Liu J., Zinn, K. E., Vance C.P., and D. L. Allan. 2005.Transgenic proteoid roots of white lupin: a vehicle for characterizing and silencing root genes involved in

adaptation to P stress.Plant Journal 44:840-853

Liu, J., Yamagishi, M., Uhde-Stone, C., Bucciarelli, B., Samac, D.A., Allan, D., and C.P.

Vance. 2005. Shoot signals and molecular regulation of P-deficiency induced genes in cluster

roots of white lupin. In: Plant Nutrition for Food Security, Human Health and Environmental Protection. Tsinghua University Press. p 94-96

Uhde-Stone, C., Zinn, K.E., Ramirez-Yánez, M., Li, A., Vance C.P. and D.L. Allan. 2003.

Nylon filter arrays reveal differential gene expression in proteoid roots of white lupin in

response to P deficiency. Plant Physiology 131:1064-1079.


Vance, C.P., Uhde-Stone, C., and D.L. Allan. 2003. Phosphorus acquisition and use: critical

adaptations by plants for securing a nonrenewable resource. Tansley Review. New

Phytologist 157:423-447.

Uhde-Stone, C., Gilbert, G., Johnson, J. M.-F, Litjens, R., Zinn, K.E., Temple, S.J., Vance,

C.P. and D.L. Allan. 2003. Acclimation of white lupin to phosphorus deficiency involves

enhanced expression of genes related to organic acid metabolism. Plant and Soil 248:99-116.

Uhde-Stone, C., Li, A., Daemen, M., Allan, D.L., and C.P. Vance. 2001. Isolation and

characterization of white lupin proteoid root expressed sequence tags (ESTs) associated with

plant hormones. p.32-33 InDevelopment in Plant and Soil Sciences: Plant Nutrition. Food

security and sustainability of agro-ecosystems through basic and applied research, Kluwer

Academic Publishers.

Liu, J., Uhde-Stone, C., Li, A., Vance, C.P., and D.L. Allan. 2001. A phosphate transporter

with enhanced expression in proteoid roots of white lupin (Lupinus albusL.). Plant and Soil


Uhde, C.,Schmidt, R., Jording, D., Selbitschka, W., and A. Pühler. 1997. Stationary phase

mutants of Sinorhizobium melilotiare impaired in stationary phase survival

or in recovery to logarithmic growth. Journal of Bacteriology 179:6432-6440.

Jording, D.,Uhde, C., Schmidt, R., and A. Pühler. 1994. The C4-dicarboxylate transport system

ofRhizobium melilotiand its role in nitrogen fixation during symbiosis with alfalfa (Medicago

sativa). InExperientia 50. Birkhäuser Verlag, CH-4010 Basel, Switzerland. 874-883.

Jording, D., Sharma, P.K., Schmidt, R., Engelke, T., Uhde, C.,and A. Pühler.1993. Regulatory

aspects of the C4-dicarboxylate transport in Rhizobium meliloti: transcriptional activation

and dependence on effective symbiosis. Journal of Plant Physiology 141:18-27.